Patents, Publication and Proceedings
PATENTS (5), PUBLICATIONS (13) AND PROCEEDINGS (40)
PATENTS: 05
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Sustain release formulation of DTPA, EDTA and their derivatives. No- 1146/DEL/2007. Dr. Aseem Bhatnagar, Dr. Ajay Kumar Singh, Nidhi Bhardwaj, Neeraj Kumar
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Vasodilator based formulation and process of preparation there of. No- 147/DEL/2009. Aseem Bhatnagar, Geeta Singh Suhag, Neeraj Kumar, Rashid Ali, Gaurav Mittal, Nakse Lal Soni, Priyanka Saxena, Neeraj Kumar
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Inhalable formulation for heavy metal poisoning. No. 2299/DEL/2009Aseem Bhatnagar, Farhan Jalees Ahamad, Neeraj Kumar, Shaheen Sultana, Gaurav Mittal, Rashid Al
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Treatment of heavy metal poisoning by inhaled phosphonates. No. 1339/DEL/2010 Aseem Bhatnagar, Shaheen Sultana, Farhan Jalees Ahmad, Gaurav Mittal, Sushma Talegaonkar, Sarwat Sultana, Thakuri Singh, Rashid Ali, Neeraj Kumar, Rashid Ali
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A formulation for treating organophosphorous poisoning and/or obstructive respiratory diseases and a process for preparing the same; No. 1136/DEL/2008 Aseem Bhatnagar, Raisuddin Ali, Farhan Jalees Ahmad, Neeraj Kumar, Priyanka Saxena, Thakuri Singh, Gaurav Kumar Jain, Gaurav Mittal and Mitra Basu.
PUBLICATIONS: 10
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Pahwa S, Pandey P, Kumar N, Fuloria S, hemalatha R; “Nutraceuticals: An alternative medical approach” on 16th Jan 2007, www.pharmainfo.net.
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Pahwa S, Fuloria NK, Kumar N, Fuloria S; “Diversified Beauty of Saccharomyces Boulardii” Pharmaceutical Reviews (2007), 5(6).
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Soni S, Gupta H, Kumar N, Nishad DK, Mittal G, Bhatnagar A; “ Biodegradable Biomaterials”, Rect Pat on biomed eng., (2010), vol 23 (1), pg 30-40.
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Mittal G, Singh T, Kumar N, Bhatnagar A, Tripathi RP, Tulsawani R, Vijayaraghavan R, Bhattacharya R “Radiolabeling and dose fixation study of oral alpha-ketoglutarate as a cyanide antidote in healthy human volunteers”. Clin Toxicol (Phila). 2010 Jul;48(6):509-15
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Mittal G, Kumar N, Rawat H, Chopra MK, Bhatnagar A; “A radiometric study of factors affecting drug output of jet nebulizers”. Indian Journal of Pharmaceutical Sciences 2010, 72(1): 31-38.
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Kumar N, Soni S, Singh T, Ahmad FJ, Bhatnagar A, Mittal G; “Edetate Calcium Disodium Nanoparticle Dry Powder Inhalation: A novel approach against heavy metal decorporation” International Journal of Pharmaceutics 416 (2011) 376– 383.
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Singh T, Kumar N, Soni S, Rawat H, Mittal G, Singh AK, Bhatnagar A “A new method for radiolabeling of human immunoglobulin-G and its biological evaluation” Journal of pharmacy and bioallied sciences, Oct-Dec 2012, vol 4, issue 4, 286-290.
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Mustafa G, Baboota S, Ali J, Kumar N, Singh T, Bhatnagar A, Ahuja, A; “Effect of Homogenization on the Fate of True Nanoemulsion in Brain Translocation: A Gamma Scintigraphic Evaluation” Science of Advanced Materials, Volume 4, Number 7, July 2012 , pp. 739-748.
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Sharma N, Kulkarni GT, Sharma A, Bhatnagar A, Kumar N “Natural mucoadhesive microspheres of Abelmoschus esculentus polysaccharide as a new carrier for nasal drug delivery” Journal of Microencapsulation Posted online on 4 Feb 2013.
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Sharma N, Kulkarnic GT, Sharma A, Bhatnagar A, Kumar N, “A novel Abelmoschus esculentus (Okra) polysaccharide based nasal mucoadhesive gel: nasal clearance and in vivo study” asianjps, 2012, Vol.7 Issue.6, Published on 20th Dec 2012. Pp. 401-406.
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Kumar N, Soni S, Singh T, Kumar A, Ahmad FJ, Bhatnagar A, “Dissolution Enhancement of A Poorly Water-Soluble Drug Using Cyclodextrin As Water-Soluble Carriers” in International Journal of Pharmacology and Pharmaceutical Sciences.
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Ali J, zafar A, Bhatnagar A, Kumar N; Ali A, “Chitosan nanoparticles amplify the ocular hypotensive effect of carteolol in rabbits” Pharmaceutical Development and Technology,
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Kumar N, Soni S, Singh T,Kumar A, Ahmad FJ, Bhatnagar A, “Development and optimization of gastro-retentive controlled release tablet of calcium-disodium edentate and its in vivo gamma scitigraphic evaluation” in International Journal of Pharmaceutics.
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Neupanea YR, Srivastavaa M, Ahmada N, Kumar N, Bhatnagar A, Kohli K, “Lipid based nanocarrier system for the potential oral delivery of decitabine: Formulation design, characterization, ex vivo, and in vivo assessment” Int. J Pharm(2014), Vol 477, Issues 1–2, Pages 601–612
PRESENTATIONS/ ABSTRACT: 40
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Fuloria S, Pahwa S, Pandey P, Kumar N; “Application of analytical techniques in the field of research of nanoparticles”, National Symposium on recent advances in analytical Sciences & application, Indian society of Analytical sciences –Delhi Chapter (Shimla) April 09-11, 2007.
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Ahmed FJ, Jain GK, Kumar N, Jain N, Iqbal Z, Talegaonkar S, Khar RK, “ Nanostructure approaches for ocular therapeutics”, International Conference of Nanoscience and Technology 2007 at Gurgaon, India, Dec 17-21, 2007.
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Kumar N, Mittal G, Singh T, Sultana S, Ali A, Ahmed FJ, Bhatnagar A; “Development and clinical evaluation of nanoparticles of ca- disodium-EDTA as a diagnostic tool for ventilation lung scintigraphy” at 35th Annual Meeting & Exposition in New York City, New York, USA on July 12-16, 2008.
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Kumar N, Mittal G, Singh T, Chopra MK, Sultana S, Ahmed FJ, Bhatnagar A; “Characterization and Clinical investigation of nanoparticles of Ca- disodium-EDTA DPI for ventilation lung scintigraphy” at sixth International Nanomedicine And Drug Delivery Symposium (Nanodds’08), held at the Leslie Dan Faculty of Pharmacy, University of Toronto (Toronto, Canada) on October 18 -19th, 2008.
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Singh G, Kumar N, Bhatnagar A, Singh H; “Estimation and comparison of salbutamol sulphate permeation from cream and patch through human skin by using gamma scintigraphy technique” at sixth International Nanomedicine And Drug Delivery Symposium (Nanodds’08), held at the Leslie Dan Faculty of Pharmacy, University of Toronto (Toronto, Canada) on October 18 -19th, 2008.
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Kumar N, Mittal G, Singh T, Chopra MK, Sultana S, Ahmed FJ and Bhatnagar A; “Development and Clinical Evaluation of Nanoparticles of Ca- disodium-EDTA as a Diagnostic Tool for Ventilation Lung Scintigraphy” at 9th Asia Oceania Congress of Nuclear Medicine and Biology, 2008 held at New Delhi India on October 31st – November 4th, 2008. Published in Ind J Nul. Med. (2008), 23 (2). Pg 158.
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Kumar N, Singh AK, Mittal G, Singh T, Mishra P, Kashyap R and Bhatnagar A; “Development of a Simplified Kit of Human Immunoglobulin- G –HYNIC for Imaging Inflammatory Foci” at 9th Asia Oceania Congress of Nuclear Medicine and Biology, 2008 held at New Delhi India on October 31st – November 4th, 2008. Published in Ind J Nul Med (2008), 23 (2). Pg. 123.
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Bhavna, Mittal G, Kumar N, Ali R, Ahmad FJ, Khar RK, Kashyap R and Bhatnagar A; “Scintigraphy of Inhaled Nanosized Salbutamol Sulphate” at 9th Asia Oceania Congress of Nuclear Medicine and Biology, 2008 held at New Delhi India on October 31st – November 4th, 2008. Published in Ind J Nul Med (2008), 23 (2). Pg. 171.
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Ali R, Soni NL, Kumar N, Ahmad E, Mittal G, Bhatnagar A; “Estimation of Drug Deposition In Lungs By Nuclear Medicine Methods” at 9th Asia Oceania Congress of Nuclear Medicine and Biology, 2008 held at New Delhi India on October 31st – November 4th, 2008.
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Kumar N, Mittal G, Singh T, Sultana S, Ahmed F A and Bhatnagar A; “Pre-Clinical Investigation of Nano-Calcium-Disodium-EDTA Dry Powder Inhaler (DPI) For Ventilation Lung Scintigraphy” at 60th Indian Pharmaceutical Congress, 2008, held at AIIMS, New Delhi on 12th -14th Dec 2008. Published in Ind J Pharmcol (2008), 40 (2), Pg S187.
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Kumar N, Mittal M, Singh T, Sultana S, Ahmed FJ, Bhatnagar A; “Development of Novel Techniques for Ventilation Lung Scintigraphy Using Nano Ca-Disodium-EDTA DPI” at 1st Nano Today Conference 2009 held at Institute of Bioengineering and Nanotechnology, Biopolis, Singapore (Singapore) from dated August 2nd -5th, 2009.
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Kumar N, Mittal M, Singh T, Sultana S, Ahmed FJ, Bhatnagar A; “Studies of Nano Calcium Di Sodium EDTA Dry Powder Inhalation (DPI) for Heavy Metal Poisoning” at 1st Nano Today Conference 2009 held at Institute of Bioengineering and Nanotechnology, Biopolis, Singapore (Singapore) from dated August 2nd -5th, 2009.
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Ali R, Soni NL, Kumar N, Bhavna, Sultana S, Mittal G, Bhatnagar A; “Evaluation and subacute toxicity studies for inhaled submicronic aerosols of 3% sodium nitrite respiratory fluids” at Second summer school on nanotechnology in advanced drug delivery, held at Centre of Pharmaceutical Nanotechnology, National Institute of Pharmaceutical Education and Research (NIPER), Punjab, India from August 10th to 14th, 2009.
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Ali R, Kumar N, Soni NL, Mittal G and Bhatnagar A; “Precorneal Reaintion and toxicity evalution of opthalmic formulation using Scientigraphy Techniques” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010. Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 81.
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Kumar N, Mittal G, Ahmed FJ, Singh T, Rawat H and Bhatnagar A; “Formulation and characterization of Ca-disodium EDTA insitu gel opthalmic formulation using Scienti graphy techniques ” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010 Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 82.
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Singh G, Soni NL, Kumar N, Mittal G, Singh H and Bhatnagar A; “Estimation and comparison of Salbultamol sulphate permeation from Cream and transdermal patch through human skin by Gamma Scintigraphy techniques ” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010 Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 92.
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Mittal G, Sultana Shaheen, Rathor V, Kumar N, Talegaunkar S, Ahmed FJ and Bhatnagar A; “Development , Charchterization and evaluation of nanosized formulation of sodium Alendronate for lung targeting ” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010. Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 93.
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Nishad DK, Singh T, Mittal G, Kumar N, Jaimini A, Sawroop K, Tiwari S and Bhatnagar A; “Radiolabelling of Betaxolol –HCl with 99mTc-pertechnetate to ascertain its bio distribution and ocular retention ” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010. Published in Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 95.
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Singh T, Mittal G, Kumar N, Nishad DK, Jaimini A, Rawat H and Bhatnagar A; “Development and charchterization of 99mTc –cefotoxime as an infection imaging radiopharmaceuticals ” at 41st Annual Conference of SNMI (SNMICON 2009) held at Jaipur, India from December 3-06, 2010 Published in Ind J Nul. Med. (2009), 24 (3&4). Pg 94.
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Kumar N, Soni S, Mittal G, Singh T, Singh A K, Bhatnagar A; “To study the 99mTecnetium-Human Immunoglobulin- G –HYNIC (99mTc-hIg G-HYNIC) for Imaging Inflammatory foci in human volunteers” at First World Conference on Nanomedicine and Drug Delivery, held at Kottayam, Kerala, India from April 16th to 18th, 2010
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Kumar N, Mittal G, Soni S, Singh T, Ahmed FA, Bhatnagar A; “Use of nano calcium Di sodium EDTA dry powder inhalation (DPI) against heavy metal poisoning as an chelation therapy” at First World Conference on Nanomedicine and Drug Delivery, held at Kottayam, Kerala, India from April 16th to 18th, 2010
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Pathan SA, Jain GK, Akhtar S, Zaidi SMA, Vohora D, Kumar N, Bhatnagar A, Ahmad FJ, Khar RK; “Nanoemulsion based Novel drug delivery system of Thymoquinone for the treatment of Epilepsy” at 3rd European Conference for Clinical Nanomedicine, CLINAM University Village, Basel, Switzerland from May 10 – 12, 2010
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Singh T, Kumar N, Mittal G, Nishad DK, Swaroop K, Seenayya G, Bhatnagar A; “Development and characterization of 99mTc -antitumor peptide for tumor scintigraphy” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25 (3). Pg 119.
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Nishad DK, Singh T, Kumar N, Swaroop K, Soni S, Sharma BG, Mittal G Bhatnagar A; “Elucidation of the mechanism of reduced uptake of 99mTc labeled bone seeking radiopharmaceutical due to iron overload” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 110
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Kumar N, Soni S, Mehra L, Mittal G, Nishad DK, Singh T, Ahmad FJ, Bhatnagar A; “Evaluation of calcium di-sodium EDTA intramuscular injection using gamma scintigraphy against heavy metal poisoning” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 81.
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Soni S, Kumar N, Mehra L, Singh T, Mittal G, Nishad DK, Sharma BG, Bhatnagar A; “In-vitro and in-vivo evaluation of Diclofenac sodium intramuscular injection using gamma scintigraphy” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 84.
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Kumar N, Aji Alex MR, Mittal G, Soni S, Nishad DK, Singh T, Ahmad FJ, Bhatnagar A; “Development and in vitro evaluation of an oral floating matrix tablet formulation of calcium di-sodium EDTA using gamma scintigraphy” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 81.
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Sharma BG, Kumar N, Soni S, Rawat HS, Singh T, Mittal G, Nishad DK, Bhatnagar A; “Development and characterization of budesonide pressurized metered dose inhaler (pMDI) using gamma scintigraphy” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 84.
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Kumar N, Dutta M, Chopra MK, Soni NL, Mittal G, Singh T, Bhavna, Bhatnagar A; “In-vitro and in-vivo analysis of radiolabeled clindamycin hydrogel by radioscintigraphic techniques” at 42nd Annual Conference of SNMI (SNMICON 2010) held at PGI Chandigarh, India from November 11-14, 2010. Published in Ind J Nul. Med. (2010), 25(3).Pg. 122.
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Kumar N, Mittal G, Ahmad FJ, Bhatnagar A; “Formulation and comparative clinical Evaluation of a Novel In-Situ Ophthalmic Drug Delivery System of INM-CE” at 62nd IPC2010 held at Manipal, Karnataka, India from December 17th-19th,2010.
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Kumar N, Mendon S, Rawat H, Bhatnagar A; “To study the lung deposition of budesonide and formoterol fumarate aerosols through pMDI technique in human volunteers by gamma scintigraphy” at 11th International Symposium of CRS-Indian Chapter on “Advances In Technology And Business Potential Of New Drug Delivery Systems” to be held in Mumbai from 16th-17th February 2011.
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Kumar N, Gupta P, Atheya UK, Mittal G, Bhatnagar A; “Use of nuclear medicine technology in evaluation of chelator based formulation against heavy metalt toxicity” at Regional Seminar on “Current Trends In Pharmaceutical And Biopharmaceuticals Industries” Conducted by Graphic Era University, Dehradun, at Graphic Era University, Uttarakhand on 23 May 2011. (Gold Medal winner).
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Agrawal P, Kumar N, Soni S, Singh T, Rawat H, Swaroop K, Tyagi A, Nishad DK, Mittal G, Bhatnagar A “Development of nano calcium Disodium EDTA – DPI against Heavy metal and radioisotope poisoning” at National Worksop on Nanotechnology for defence application (NWNDA 2011) organized by Solid state physics laboratory and Group forcasting & analysis of system & technologies at SSPL, DRDO lab, Timarpur, Delhi from 16th to 17th Nov 2011
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Sharma BG, Bhavna, Kumar N, Singh T, Nishad DK, Tyagi A, Mittal G, Bhatnagar A “Development of nano salbutamol sulphate DPI for the treatment of astma & ling injuries” at National Worksop on Nanotechnology for defence application (NWNDA 2011) organized by Solid state physics laboratory and Group forcasting & analysis of system & technologies at SSPL, DRDO lab, Timarpur, Delhi from 16th to 17th Nov 2011
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Sharma BG, Ali R, Kumar N, Nishad DK, Singh T, Tyagi A, Mittal G, Bhatnagar A “Effect of Hypobaric hypoxia induced stress on physiological parameters: in vivo evaluation of Gastrointestinal motility in rats” at XXXI Annual conference of society of toxicology (STOX), India & International symposium on current trends in environmental toxicology organized by Department of zoology, The IIS University, Jaipur, Rajesthan from 22nd to 24th Dec 2011.
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Kumar N, Soni S, Mendon S, Singh T, Rawat H, Nishad DK, Mittal G, Bhatnagar A “To study the lung deposition of budesonide and formoterol fumrate pMDI in healthy human volunteers by gamma scintigraphy technique” at International Symposium on airway diseases: etiology to clinic held organized by Daiichi Sankyo India Pharma Pvt. Ltd and Ranbaxy Laboratories ltd. at Ranbaxy R&D-3, Gurgaon, India on 24th &25th Feb.2012.
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Soni S, Kumar N, Sharma GB, Mittal R, Vijyan TA, Singh T, Mittal G, Chillar N, Bhatnagar A “Comparative evaluation of dry powder inhaler devices on the basis of respirable fraction in healthy human volunteers using gamma scientigraphy techniques at International Symposium on airway diseases: etiology to clinic held organized by Daiichi Sankyo India Pharma Pvt. Ltd and Ranbaxy Laboratories ltd. at Ranbaxy R&D-3, Gurgaon, India on 24th &25th Feb.2012.
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Kumar N, Ali R, Soni NL, Mittal G and Bhatnagar A; “Development, Toxicity Evaluation and pre-corneal retention behaviour of a noval chelator based ophthalmic formulation using gamma scintigraphy” at 2nd world congress on Ga-68 (Generators and Noval Radiopharmaceuticals), Molecular Imaging (PET/CT), Targeted Radionuclide Therapy and dosimetry: On the way to personalised Medicine, held at PGI Chandigarh, India from February 28 - March 2, 2013,. Published in WJ Nul. Med. (2013), 12 (S-1). Pg 98-99.
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Singh T, Rathor VPS, Soni S, Kumar N, Sawroop K, Mittal G, Chugh P and Bhatnagar A; “Radiolabelling and Biologicals evaluation of Sildenafil Citrate respiratory fluid as a potential treatment of pulmonary hypertension” at 2nd world congress on Ga-68 (Generators and Noval Radiopharmaceuticals), Molecular Imaging (PET/CT), Targeted Radionuclide Therapy and dosimetry: On the way to personalised Medicine, held at PGI Chandigarh, India from February 28 - March 2, 2013,. Published in WJ Nul. Med. (2013), 12 (S-1). Pg 101.
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Soni S, Kumar N, Nishad DK, Chaudhury NK, Basu M, Bhatnagar A and Chhillar N; “Identification of novel non-invasive biochemical marker for acute radiation injury: A preliminary Study” at 2nd world congress on Ga-68 (Generators and Noval Radiopharmaceuticals), Molecular Imaging (PET/CT), Targeted Radionuclide Therapy and dosimetry: On the way to personalised Medicine, held at PGI Chandigarh, India from February 28 - March 2, 2013,. Published in WJ Nul. Med. (2013), 12 (S-1). Pg 101.